Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems

Aging compromises hematopoietic and immune system functions, making older adults especially susceptible to hematopoietic failure, infections and tumor development, and thus representing an important medical target for a broad range of diseases. During aging, hematopoietic stem cells (HSCs) lose thei...

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Veröffentlicht in:	Nature aging 2023-09, Vol.3 (9), p.1057-1066
Hauptverfasser:	Girotra, Mukul, Chiang, Yi-Hsuan, Charmoy, Melanie, Ginefra, Pierpaolo, Hope, Helen Carrasco, Bataclan, Charles, Yu, Yi-Ru, Schyrr, Frederica, Franco, Fabien, Geiger, Hartmut, Cherix, Stephane, Ho, Ping-Chih, Naveiras, Olaia, Auwerx, Johan, Held, Werner, Vannini, Nicola
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Stem cells
Online-Zugang:	Volltext
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