Proteolytically Stable ααγ-Hybrid Peptides Inhibit the Aggregation and Cytotoxicity of Aβ42

The recent approval of antibody-based therapy for targeting the clearance of amyloid plaques fuels the research in designing small molecules and peptide inhibitors to target the aggregation of Aβ-peptides. Here, we report that the 15-residue ααγ-hybrid peptide not only inhibits the aggregation of so...

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Veröffentlicht in:ACS chemical neuroscience 2023-09, Vol.14 (18), p.3398-3408
Hauptverfasser: Puneeth Kumar, DRGKoppalu R., Nalawade, Sachin A., Pahan, Saikat, Singh, Manjeet, Senapati, Dillip K., Roy, Souvik, Dey, Sanjit, Toraskar, Sandip U., Raghothama, Srinivasarao, Gopi, Hosahudya N.
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Sprache:eng
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