The 2′-hydroxy group of flavin mononucleotide influences the catalytic function and promiscuity of the flavoprotein iodotyrosine dehalogenase

The isoalloxazine ring system of the flavin cofactor is responsible for much of the catalytic power and diversity associated with flavoproteins. While the specificity of these enzymes is greatly influenced by the surrounding protein environment, the ribityl group of the cofactor may also participate...

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Veröffentlicht in:	RSC chemical biology 2023-08, Vol.4 (9), p.698-75
Hauptverfasser:	Kozyryev, Anton, Boucher, Petrina A, Quiñones-Jurgensen, Carla M, Rokita, Steven E
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry
Online-Zugang:	Volltext
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