LncRNA RPLP0P2 Promotes Colorectal Cancer Proliferation and Invasion via the miR-129-5p/Zinc Finger and BTB Domain-Containing 20 Axis

We previously reported that long non-coding RNA (lncRNA) RPLP0P2 is involved in the progression of colorectal cancer (CRC); however, its molecular mechanisms in CRC remain unclear. In this study, we observed that RPLP0P2 was upregulated in CRC tissues and cell lines. Cell viability was measured usin...

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Veröffentlicht in:	Biochemical genetics 2024-06, Vol.62 (3), p.1556-1576
Hauptverfasser:	Yuan, Hang, Yu, Peng, Wan, Zi-Ang, Chen, Bing-Chen, Tu, Shi-Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticancer properties Assaying Biochemistry Biomedical and Life Sciences Biomedicine cadherins Cancer Cell Line, Tumor Cell migration Cell Proliferation Cell viability Colorectal cancer Colorectal carcinoma colorectal neoplasms Colorectal Neoplasms - genetics Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology E-cadherin Female fluorescent antibody technique Gene Expression Regulation, Neoplastic Human Genetics Humans Immunofluorescence Male Medical Microbiology Mice Mice, Inbred BALB C Mice, Nude MicroRNAs - genetics MicroRNAs - metabolism Molecular modelling N-Cadherin Neoplasm Invasiveness Non-coding RNA oncogenes Original Article RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Transcription Factors - genetics Transcription Factors - metabolism Tumors Vimentin Wound healing Xenotransplantation Zinc zinc finger motif Zinc finger proteins Zinc Fingers Zoology
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