The Role of ONECUT1 Variants in Monogenic and Type 2 Diabetes Mellitus

ONECUT1 (also known as HNF6) is a transcription factor involved in pancreatic development and β-cell function. Recently, biallelic variants in ONECUT1 were reported as a cause of neonatal diabetes mellitus (NDM) in two subjects, and missense monoallelic variants were associated with type 2 diabetes...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2023-11, Vol.72 (11), p.1729-1734
Hauptverfasser:	Russ-Silsby, James, Patel, Kashyap A., Laver, Thomas W., Hawkes, Gareth, Johnson, Matthew B., Wakeling, Matthew N., Patil, Prashant P., Hattersley, Andrew T., Flanagan, Sarah E., Weedon, Michael N., De Franco, Elisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Beta cells Biobanks Diabetes Diabetes mellitus (non-insulin dependent) Neonates Risk factors
Online-Zugang:	Volltext
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