Non-steroidal mineralocorticoid receptor antagonists in heart failure
Novel non-steroidal mineralocorticoid receptor antagonists (MRAs) have improved pharmacological properties compared with steroidal MRAs. Among the non-steroidal MRAs, finerenone has been approved for patients with chronic kidney disease who have diabetes mellitus and has demonstrated favourable safe...
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Veröffentlicht in: | Nature reviews cardiology 2023-10, Vol.20 (10), p.645-646 |
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creator | Filippatos, Gerasimos Farmakis, Dimitrios |
description | Novel non-steroidal mineralocorticoid receptor antagonists (MRAs) have improved pharmacological properties compared with steroidal MRAs. Among the non-steroidal MRAs, finerenone has been approved for patients with chronic kidney disease who have diabetes mellitus and has demonstrated favourable safety and promising early results in patients with heart failure. |
doi_str_mv | 10.1038/s41569-023-00922-x |
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subjects | 692/699/75/230 692/700/565/1436 Cardiac Imaging Cardiac Surgery Cardiology Clinical Outlook Diabetes Ejection fraction Enzymes Heart failure Hospitalization Hyperkalemia Kidney diseases Medicine Medicine & Public Health |
title | Non-steroidal mineralocorticoid receptor antagonists in heart failure |
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