MiR-452-5p facilitates retinoblastoma cell growth and invasion via the SOCS3/JAK2/STAT3 pathway

Retinoblastoma (RB) is an intraocular tumor in children. Accumulated evidence confirms that microRNAs (miRNAs) exert critical functions in RB. This research aimed to investigate the miR-452-5p function in RB. MiR-452-5p expressions in RB were tested with quantitative real-time polymerase chain react...

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Veröffentlicht in:	Journal of biochemical and molecular toxicology 2023-12, Vol.37 (12), p.e23501-e23501
Hauptverfasser:	Wu, Laiwei, Huang, Guoqiang, Hong, Huifeng, Xu, Xiangzhou, Lu, Xiaohe, Li, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Assaying Bioinformatics Cell growth Cell Line, Tumor Cell Proliferation Child Flow cytometry Gene Expression Regulation, Neoplastic Humans Immunohistochemistry In vivo methods and tests Janus kinase Janus kinase 2 Janus Kinase 2 - genetics Janus Kinase 2 - metabolism Kinases Mice Mice, Nude MicroRNAs MicroRNAs - metabolism miRNA Polymerase chain reaction Reporter gene Retinal Neoplasms - genetics Retinal Neoplasms - pathology Retinoblastoma Retinoblastoma - genetics Retinoblastoma - pathology Signal Transduction Stat3 protein STAT3 Transcription Factor - genetics STAT3 Transcription Factor - metabolism Suppressor of Cytokine Signaling 3 Protein - genetics Suppressor of Cytokine Signaling 3 Protein - metabolism Suppressors Transducers Tumors Xenotransplantation
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