Parathyroid Hormone Inhibits Fatty Infiltration and Muscle Atrophy After Rotator Cuff Tear by Browning of Fibroadipogenic Progenitors in a Rodent Model

Background: Progressive fatty infiltration and muscle atrophy after rotator cuff tears lead to tendon repair failure and poor outcomes. Fibro-adipogenic progenitors (FAPs) are involved in fatty infiltration and muscle homeostasis of skeletal muscle. Inducing FAP differentiation into brown adipocyte–...

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Veröffentlicht in:The American journal of sports medicine 2023-10, Vol.51 (12), p.3251-3260
Hauptverfasser: Iio, Ryosuke, Manaka, Tomoya, Takada, Naoki, Orita, Kumi, Nakazawa, Katsumasa, Hirakawa, Yoshihiro, Ito, Yoichi, Nakamura, Hiroaki
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Sprache:eng
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