Chiral Lewis Acid-Catalyzed Asymmetric Multicomponent Michael Reaction through [1,2]-Phospha-Brook Rearrangement

The multicomponent catalytic asymmetric Pudovik addition/[1,2]-phospha-Brook rearrangement/Michael reaction sequence of isatins, phosphites, and 4-oxobutenoates was realized. A series of oxindole derivatives containing two contiguous stereocenters was obtained in high yields and excellent stereosele...

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Veröffentlicht in:	Organic letters 2023-09, Vol.25 (34), p.6262-6266
Hauptverfasser:	Lin, Qianchi, Wang, Siyuan, Weng, Rui, Cao, Weidi, Feng, Xiaoming
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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