Photoactivated DNA Nanodrugs Damage Mitochondria to Improve Gene Therapy for Reversing Chemoresistance

Multidrug resistance (MDR) is a major cause of chemotherapy failure in oncology, and gene therapy is an excellent measure to reverse MDR. However, conventional gene therapy only modulates the expression of MDR-associated proteins but hardly affects their existing function, thus limiting the efficien...

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Veröffentlicht in:	ACS nano 2023-09, Vol.17 (17), p.16923-16934
Hauptverfasser:	Wang, Danyu, Yi, Hua, Geng, Shizhen, Jiang, Chuanmei, Liu, Jingwen, Duan, Jie, Zhang, Zhenzhong, Shi, Jinjin, Song, Haiwei, Guo, Zhenzhen, Zhang, Kaixiang
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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