Boric Acid Alleviates Gastric Ulcer by Regulating Oxidative Stress and Inflammation-Related Multiple Signaling Pathways

Oxidative stress and inflammation have pivotal roles in gastric ulcer development caused by alcohol consumption. Trace element boric acid taken into the human and animal body from dietary sources displays strong antioxidant and anti-inflammatory functions. However, the mechanisms underlying these ac...

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Veröffentlicht in:	Biological trace element research 2024-05, Vol.202 (5), p.2124-2132
Hauptverfasser:	Gündoğdu, Ayşe Çakır, Özbayer, Cansu, Kar, Fatih
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Alcohols AMP-Activated Protein Kinases Animals Anti-Ulcer Agents - pharmacology Anti-Ulcer Agents - therapeutic use Antioxidants Antioxidants - metabolism Biochemistry Biomedical and Life Sciences Biotechnology Boric acid Boric Acids Effectiveness ELISA Enzyme-linked immunosorbent assay Ethanol Ethanol - adverse effects Evaluation Gastric Mucosa Gene expression Histopathology Homocysteine Homocysteine - metabolism Humans Inflammation Inflammation - chemically induced Inflammation - drug therapy Inflammation - metabolism Interleukin 6 Interleukin-6 - metabolism Janus kinase 2 Lesions Life Sciences Necrosis Nucleotide sequence Nutrition Oncology Oxidation Oxidative Stress Pretreatment Rats Reactive oxygen species Semaphorin-3A - metabolism Semaphorin-3A - pharmacology Semaphorin-3A - therapeutic use Semaphorins Signal Transduction Stat3 protein Stomach Ulcer - chemically induced Stomach Ulcer - drug therapy Stomach Ulcer - prevention & control Trace elements Trace elements (nutrients) Tumor necrosis factor-TNF Tumor necrosis factor-α Ulcers Valence
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