Elemental mass spectrometry to study metallo-transcriptomic changes during the in vitro degeneration of the retinal pigment epithelium

Trace elements play crucial roles in cellular biology. Their improper homeostasis may contribute to the progress of eye diseases, exacerbated during ageing. The retinal pigment epithelium (RPE) is progressively deteriorated during age-related neurodegeneration and metal homeostasis may be compromise...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2024-05, Vol.416 (11), p.2699-2710
Hauptverfasser:	Álvarez-Barrios, Ana, Álvarez, Lydia, Pereiro, Rosario, González-Iglesias, Héctor
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging (metallurgy) Analytical Chemistry Antioxidants Antioxidants - metabolism Biochemistry Biology Cell culture Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Copper Cytosol Degeneration Elemental Mass Spectrometry for Bioanalysis Epithelium Eye diseases Flow injection analysis Food Science Gene Expression Profiling Gene sequencing Homeostasis Humans Immunocytochemistry Inductively coupled plasma Infant Laboratory Medicine Magnesium Mass spectrometry Mass Spectrometry - methods Mass spectroscopy Metallography Metals Metals - metabolism Molecular biology Monitoring/Environmental Analysis Neurodegeneration Pigments Research Paper Retina Retinal Pigment Epithelium Scientific imaging Trace Elements Transcriptomics
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