Leukoreduction of red blood cell units decreases dysregulatory micro RNAs during routine storage: An observational study with In-silico analysis

Red Blood cells (RBCs) bring about harmful consequences during storage. MicroRNA (miRNA) dysregulation in stored RBCs could represent potential biomarkers of storage lesions. Although leukoreduction prevents damage to RBCs, it is uncertain whether leukoreduction of RBCs would impact the dysregulatio...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2023-09, Vol.63 (9), p.1747-1757
Hauptverfasser:	Mukherjee, Somnath, Das, Potnuru Gouri Shankar, Prakash, Satya, Ghosh, Amit, Priyadarshini, Trishna, Purkait, Suvendu
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biomarkers Blood Damage prevention Erythrocytes Impact damage In vivo methods and tests MicroRNAs miRNA mRNA Observational studies Senescence Storage
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