Topical Tranexamic Acid in Primary Breast Augmentation Surgery: Short- and Long-term Outcomes
Abstract Background Breast augmentation mammaplasty (BAM) remains the most popular cosmetic procedure done worldwide. Bleeding in this procedure increases the chance of capsular contracture. Tranexamic acid (TXA), an antifibrinolytic, has been widely used by other surgical specialties to reduce blee...
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| Veröffentlicht in: | Aesthetic surgery journal 2023-12, Vol.44 (1), p.23-27 |
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| creator | Lonie, Sarah Abesamis, Gerald Marion Law, Jenaleen Mohaghegh, Mohammad Hassan Vickery, Karen Deva, Anand Tavakoli, Kourosh |
| description | Abstract
Background
Breast augmentation mammaplasty (BAM) remains the most popular cosmetic procedure done worldwide. Bleeding in this procedure increases the chance of capsular contracture. Tranexamic acid (TXA), an antifibrinolytic, has been widely used by other surgical specialties to reduce bleeding.
Objectives
We aimed to evaluate the use of TXA in BAM surgery.
Methods
This was a single-surgeon case series of all patients who underwent primary BAM from March 2017 to March 2018 and received topical TXA spray to the implant pocket before implant insertion. Early postoperative complications and long-term outcomes, such as capsular contracture and revisional surgery, were recorded and described.
Results
Two hundred and eighty-eight patients were included in the study with an overall complication rate of 2.8% over 5 years. No patients had postoperative bleeding or hematoma formation. One patient had a seroma, managed with ultrasound drainage. Complications requiring reoperation included rippling (3, 1.0%), pocket revision (2, 0.7%), capsule contracture (1, 0.3%) and rupture (1, 0.3%).
Conclusions
This study highlights the safety and potential benefits of the use of topical TXA in breast augmentation, with low bleeding and capsular contracture rates.
Level of Evidence: 4 |
| doi_str_mv | 10.1093/asj/sjad219 |
| format | Article |
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Background
Breast augmentation mammaplasty (BAM) remains the most popular cosmetic procedure done worldwide. Bleeding in this procedure increases the chance of capsular contracture. Tranexamic acid (TXA), an antifibrinolytic, has been widely used by other surgical specialties to reduce bleeding.
Objectives
We aimed to evaluate the use of TXA in BAM surgery.
Methods
This was a single-surgeon case series of all patients who underwent primary BAM from March 2017 to March 2018 and received topical TXA spray to the implant pocket before implant insertion. Early postoperative complications and long-term outcomes, such as capsular contracture and revisional surgery, were recorded and described.
Results
Two hundred and eighty-eight patients were included in the study with an overall complication rate of 2.8% over 5 years. No patients had postoperative bleeding or hematoma formation. One patient had a seroma, managed with ultrasound drainage. Complications requiring reoperation included rippling (3, 1.0%), pocket revision (2, 0.7%), capsule contracture (1, 0.3%) and rupture (1, 0.3%).
Conclusions
This study highlights the safety and potential benefits of the use of topical TXA in breast augmentation, with low bleeding and capsular contracture rates.
Level of Evidence: 4</description><identifier>ISSN: 1090-820X</identifier><identifier>ISSN: 1527-330X</identifier><identifier>EISSN: 1527-330X</identifier><identifier>DOI: 10.1093/asj/sjad219</identifier><identifier>PMID: 37427875</identifier><language>eng</language><publisher>US: Oxford University Press</publisher><subject>Breast Implantation - adverse effects ; Breast Implantation - methods ; Breast Implants - adverse effects ; Contracture - etiology ; Contracture - surgery ; Female ; Follow-Up Studies ; Humans ; Mammaplasty - methods ; Retrospective Studies ; Tranexamic Acid - adverse effects</subject><ispartof>Aesthetic surgery journal, 2023-12, Vol.44 (1), p.23-27</ispartof><rights>The Author(s) 2023. Published by Oxford University Press on behalf of The Aesthetic Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2023</rights><rights>The Author(s) 2023. Published by Oxford University Press on behalf of The Aesthetic Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c208t-bcf950b921f243f8699fc59b2cd49dc0c6735d1454bc4a42dae640f1940492383</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37427875$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lonie, Sarah</creatorcontrib><creatorcontrib>Abesamis, Gerald Marion</creatorcontrib><creatorcontrib>Law, Jenaleen</creatorcontrib><creatorcontrib>Mohaghegh, Mohammad Hassan</creatorcontrib><creatorcontrib>Vickery, Karen</creatorcontrib><creatorcontrib>Deva, Anand</creatorcontrib><creatorcontrib>Tavakoli, Kourosh</creatorcontrib><title>Topical Tranexamic Acid in Primary Breast Augmentation Surgery: Short- and Long-term Outcomes</title><title>Aesthetic surgery journal</title><addtitle>Aesthet Surg J</addtitle><description>Abstract
Background
Breast augmentation mammaplasty (BAM) remains the most popular cosmetic procedure done worldwide. Bleeding in this procedure increases the chance of capsular contracture. Tranexamic acid (TXA), an antifibrinolytic, has been widely used by other surgical specialties to reduce bleeding.
Objectives
We aimed to evaluate the use of TXA in BAM surgery.
Methods
This was a single-surgeon case series of all patients who underwent primary BAM from March 2017 to March 2018 and received topical TXA spray to the implant pocket before implant insertion. Early postoperative complications and long-term outcomes, such as capsular contracture and revisional surgery, were recorded and described.
Results
Two hundred and eighty-eight patients were included in the study with an overall complication rate of 2.8% over 5 years. No patients had postoperative bleeding or hematoma formation. One patient had a seroma, managed with ultrasound drainage. Complications requiring reoperation included rippling (3, 1.0%), pocket revision (2, 0.7%), capsule contracture (1, 0.3%) and rupture (1, 0.3%).
Conclusions
This study highlights the safety and potential benefits of the use of topical TXA in breast augmentation, with low bleeding and capsular contracture rates.
Level of Evidence: 4</description><subject>Breast Implantation - adverse effects</subject><subject>Breast Implantation - methods</subject><subject>Breast Implants - adverse effects</subject><subject>Contracture - etiology</subject><subject>Contracture - surgery</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Mammaplasty - methods</subject><subject>Retrospective Studies</subject><subject>Tranexamic Acid - adverse effects</subject><issn>1090-820X</issn><issn>1527-330X</issn><issn>1527-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1LwzAYh4Mobk5P3iUnEaTubZJ-xNscfsFgwibsIiVN0tnRNjNJwf33dnR69PS-h4cHfg9ClyHchcDpWLjN2G2EIiE_QsMwIklAKayOux84BCmB1QCdObcB6PCYnaIBTRhJ0iQaoo-l2ZZSVHhpRaO_RV1KPJGlwmWD32xZC7vDD1YL5_GkXde68cKXpsGL1q613d3jxaexPsCiUXhmmnXgta3xvPXS1Nqdo5NCVE5fHO4IvT89LqcvwWz-_DqdzAJJIPVBLgseQc5JWBBGizTmvJARz4lUjCsJMk5opEIWsVwywYgSOmZQhJwB44SmdIRueu_Wmq9WO5_VpZO6qrpNpnUZSSPGKADZo7c9Kq1xzuoi2_YzsxCyfc-s65kdenb01UHc5rVWf-xvwA647gHTbv81_QBECn7f</recordid><startdate>20231214</startdate><enddate>20231214</enddate><creator>Lonie, Sarah</creator><creator>Abesamis, Gerald Marion</creator><creator>Law, Jenaleen</creator><creator>Mohaghegh, Mohammad Hassan</creator><creator>Vickery, Karen</creator><creator>Deva, Anand</creator><creator>Tavakoli, Kourosh</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20231214</creationdate><title>Topical Tranexamic Acid in Primary Breast Augmentation Surgery: Short- and Long-term Outcomes</title><author>Lonie, Sarah ; Abesamis, Gerald Marion ; Law, Jenaleen ; Mohaghegh, Mohammad Hassan ; Vickery, Karen ; Deva, Anand ; Tavakoli, Kourosh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c208t-bcf950b921f243f8699fc59b2cd49dc0c6735d1454bc4a42dae640f1940492383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Breast Implantation - adverse effects</topic><topic>Breast Implantation - methods</topic><topic>Breast Implants - adverse effects</topic><topic>Contracture - etiology</topic><topic>Contracture - surgery</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Mammaplasty - methods</topic><topic>Retrospective Studies</topic><topic>Tranexamic Acid - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lonie, Sarah</creatorcontrib><creatorcontrib>Abesamis, Gerald Marion</creatorcontrib><creatorcontrib>Law, Jenaleen</creatorcontrib><creatorcontrib>Mohaghegh, Mohammad Hassan</creatorcontrib><creatorcontrib>Vickery, Karen</creatorcontrib><creatorcontrib>Deva, Anand</creatorcontrib><creatorcontrib>Tavakoli, Kourosh</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Aesthetic surgery journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lonie, Sarah</au><au>Abesamis, Gerald Marion</au><au>Law, Jenaleen</au><au>Mohaghegh, Mohammad Hassan</au><au>Vickery, Karen</au><au>Deva, Anand</au><au>Tavakoli, Kourosh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Topical Tranexamic Acid in Primary Breast Augmentation Surgery: Short- and Long-term Outcomes</atitle><jtitle>Aesthetic surgery journal</jtitle><addtitle>Aesthet Surg J</addtitle><date>2023-12-14</date><risdate>2023</risdate><volume>44</volume><issue>1</issue><spage>23</spage><epage>27</epage><pages>23-27</pages><issn>1090-820X</issn><issn>1527-330X</issn><eissn>1527-330X</eissn><abstract>Abstract
Background
Breast augmentation mammaplasty (BAM) remains the most popular cosmetic procedure done worldwide. Bleeding in this procedure increases the chance of capsular contracture. Tranexamic acid (TXA), an antifibrinolytic, has been widely used by other surgical specialties to reduce bleeding.
Objectives
We aimed to evaluate the use of TXA in BAM surgery.
Methods
This was a single-surgeon case series of all patients who underwent primary BAM from March 2017 to March 2018 and received topical TXA spray to the implant pocket before implant insertion. Early postoperative complications and long-term outcomes, such as capsular contracture and revisional surgery, were recorded and described.
Results
Two hundred and eighty-eight patients were included in the study with an overall complication rate of 2.8% over 5 years. No patients had postoperative bleeding or hematoma formation. One patient had a seroma, managed with ultrasound drainage. Complications requiring reoperation included rippling (3, 1.0%), pocket revision (2, 0.7%), capsule contracture (1, 0.3%) and rupture (1, 0.3%).
Conclusions
This study highlights the safety and potential benefits of the use of topical TXA in breast augmentation, with low bleeding and capsular contracture rates.
Level of Evidence: 4</abstract><cop>US</cop><pub>Oxford University Press</pub><pmid>37427875</pmid><doi>10.1093/asj/sjad219</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Aesthetic surgery journal, 2023-12, Vol.44 (1), p.23-27 |
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| language | eng |
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| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| subjects | Breast Implantation - adverse effects Breast Implantation - methods Breast Implants - adverse effects Contracture - etiology Contracture - surgery Female Follow-Up Studies Humans Mammaplasty - methods Retrospective Studies Tranexamic Acid - adverse effects |
| title | Topical Tranexamic Acid in Primary Breast Augmentation Surgery: Short- and Long-term Outcomes |
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