Dopamine release and negative valence gated by inhibitory neurons in the laterodorsal tegmental nucleus

GABAergic neurons in the laterodorsal tegmental nucleus (LDTGABA) encode aversion by directly inhibiting mesolimbic dopamine (DA). Yet, the detailed cellular and circuit mechanisms by which these cells relay unpleasant stimuli to DA neurons and regulate behavioral output remain largely unclear. Here...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2023-10, Vol.111 (19), p.3102-3118.e7
Hauptverfasser:	Du, Yonglan, Zhou, Siyao, Ma, Chenyan, Chen, Hui, Du, Ana, Deng, Guochuang, Liu, Yige, Tose, Amanda J., Sun, Li, Liu, Yijun, Wu, Hangjun, Lou, Huifang, Yu, Yan-qin, Zhao, Ting, Lammel, Stephan, Duan, Shumin, Yang, Hongbin
Format:	Artikel
Sprache:	eng
Schlagworte:	aversion dopamine GABAergic subtypes hypothalamus laterodorsal tegmental nucleus motivated behaviors nucleus accumbens pain ventral tegmental area
Online-Zugang:	Volltext
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