Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice

Maternal lipopolysaccharide (LPS) exposure during pregnancy has been related to IUGR. Here, we explored whether paternal LPS exposure before mating impaired fetal development. All male mice except controls were intraperitoneally injected with LPS every other day for a total of five injections. The n...

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Veröffentlicht in:Archives of toxicology 2023-11, Vol.97 (11), p.2929-2941
Hauptverfasser: Jiang, Pei-Ying, Lin, Shuai, Liu, Jie-Ru, Liu, Yan, Zheng, Li-Ming, Hong, Qiang, Fan, Yi-Jun, Xu, De-Xiang, Chen, Yuan-Hua
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Sprache:eng
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