Frizzled‐9 triggers actin polymerization and activates mechano‐transducer YAP to rescue simulated microgravity‐induced osteoblast dysfunction

Long‐term spaceflight can result in bone loss and osteoblast dysfunction. Frizzled‐9 (Fzd9) is a Wnt receptor of the frizzled family that is vital for osteoblast differentiation and bone formation. In the present study, we elucidated whether Fzd9 plays a role in osteoblast dysfunction induced by sim...

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Veröffentlicht in:	The FASEB journal 2023-09, Vol.37 (9), p.e23147-n/a
Hauptverfasser:	Shi, Qiusheng, Gui, Jinpeng, Sun, Lianwen, Song, Yaxin, Na, Jing, Zhang, Jingyi, Fan, Yubo, Zheng, Lisha
Format:	Artikel
Sprache:	eng
Schlagworte:	Frizzled‐9 nuclear pore osteoblast dysfunction simulated microgravity YAP
Online-Zugang:	Volltext
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