Myocardial revascularization failure among patients requiring cardiac catheterization and secondary revascularization in contemporary clinical practice: Results of the REVASEC multicenter registry
BackgroundMyocardial revascularization failure (MRF) and Secondary revascularization (SR) are contemporary interventional cardiology challenges.AimTo investigate the characteristics, management, and prognosis of patients with myocardial revascularization failure (MRF) and need for secondary revascul...
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| creator | Salinas, Pablo García‐Camarero, Tamara Jimenez‐Kockar, Marcelo Regueiro, Ander García‐Blas, Sergio Gomez‐Menchero, Antonio E. Ojeda, Soledad Vilchez‐Tschischke, Jean Paul Amat‐Santos, Ignacio Díez‐Gil, Jose Luis Rondán, Juan Lozano Ruiz‐Poveda, Fernando de Miguel Castro, Antonio Manzano, Maria C. Pascual‐Tejerina, Virginia Cruz‐González, Ignacio García Perez‐Velasco, Javier Fernández‐Diaz, Jose A. Escaned, Javier |
| description | BackgroundMyocardial revascularization failure (MRF) and Secondary revascularization (SR) are contemporary interventional cardiology challenges.AimTo investigate the characteristics, management, and prognosis of patients with myocardial revascularization failure (MRF) and need for secondary revascularization (SR) in contemporary practice.MethodsThe REVASEC study is a prospective registry (NCT03349385), which recruited patients with prior revascularization referred for coronary angiography at 19 centers. The primary endpoint is a patient‐oriented composite (POCE) at 1 year, including death, myocardial infarction, or repeat revascularization.ResultsA total of 869 patients previously revascularized by percutaneous intervention (83%) or surgery (17%) were recruited. MRF was found in 83.7% (41.1% stent/graft failure, 32.1% progression of coronary disease, and 10.5% residual disease). SR was performed in 70.1%, preferably by percutaneous intervention (95%). The POCE rate at 1 year was 14% in the overall cohort, with 6.4% all‐cause death. In the multivariate analysis, lower POCE rates were found in the groups without MRF (9.4%) and with disease progression (11%) compared with graft/stent failure (17%) and residual disease (18%), hazard ratio 0.67 (95% confidence interval: 0.45–0.99), p = 0.043. At 1 year, the SR group had less chronic persistent angina (19% vs. 34%, p |
| doi_str_mv | 10.1002/ccd.30804 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2851870051</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2851870051</sourcerecordid><originalsourceid>FETCH-LOGICAL-c250t-73a2c5b5ddc365dfa3b6c1cf0a11931cf8b641cc6630153231ab6e9555108d553</originalsourceid><addsrcrecordid>eNptkU1LAzEQhhdRUKsH_0HAix5a89Gku95KqR-gCH7hbUlns5qym6xJVqi_zx_maMWDeJph5nnfDHmz7IDREaOUnwBUI0FzOt7IdpjkfDjh6mnzp2fFWG1nuzEuKaWF4sVO9nG98qBDZXVDgnnTEfpGB_uuk_WO1No2fTBEt949kw6HxqWI4Gtvg8XRWgpY04tJ5leoXUWiAe8qHVb_GFtHcJlM2_nwRUBjnQW8oQsakgVzSm5N7Bt8zNcEvcnt_HF6N5-RFoe4R21A32cbU1jtZVu1bqLZ_6mD7OFsfj-7GF7dnF_OpldD4JKm4URoDnIhqwqEklWtxUIBg5pqxgqBTb5QYwaglKBMCi6YXihTSCkZzSspxSA7Wvt2wb_2JqaytRFM02hnfB9LnkuWTyiVDNHDP-jS98HhdUhhJiznY4XU8ZqC4GMMpi67YFv8kJLR8ivPEvMsv_MUn1B1mNs</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2872618246</pqid></control><display><type>article</type><title>Myocardial revascularization failure among patients requiring cardiac catheterization and secondary revascularization in contemporary clinical practice: Results of the REVASEC multicenter registry</title><source>Access via Wiley Online Library</source><creator>Salinas, Pablo ; García‐Camarero, Tamara ; Jimenez‐Kockar, Marcelo ; Regueiro, Ander ; García‐Blas, Sergio ; Gomez‐Menchero, Antonio E. ; Ojeda, Soledad ; Vilchez‐Tschischke, Jean Paul ; Amat‐Santos, Ignacio ; Díez‐Gil, Jose Luis ; Rondán, Juan ; Lozano Ruiz‐Poveda, Fernando ; de Miguel Castro, Antonio ; Manzano, Maria C. ; Pascual‐Tejerina, Virginia ; Cruz‐González, Ignacio ; García Perez‐Velasco, Javier ; Fernández‐Diaz, Jose A. ; Escaned, Javier</creator><creatorcontrib>Salinas, Pablo ; García‐Camarero, Tamara ; Jimenez‐Kockar, Marcelo ; Regueiro, Ander ; García‐Blas, Sergio ; Gomez‐Menchero, Antonio E. ; Ojeda, Soledad ; Vilchez‐Tschischke, Jean Paul ; Amat‐Santos, Ignacio ; Díez‐Gil, Jose Luis ; Rondán, Juan ; Lozano Ruiz‐Poveda, Fernando ; de Miguel Castro, Antonio ; Manzano, Maria C. ; Pascual‐Tejerina, Virginia ; Cruz‐González, Ignacio ; García Perez‐Velasco, Javier ; Fernández‐Diaz, Jose A. ; Escaned, Javier ; REVASEC working group (collaborators)</creatorcontrib><description>BackgroundMyocardial revascularization failure (MRF) and Secondary revascularization (SR) are contemporary interventional cardiology challenges.AimTo investigate the characteristics, management, and prognosis of patients with myocardial revascularization failure (MRF) and need for secondary revascularization (SR) in contemporary practice.MethodsThe REVASEC study is a prospective registry (NCT03349385), which recruited patients with prior revascularization referred for coronary angiography at 19 centers. The primary endpoint is a patient‐oriented composite (POCE) at 1 year, including death, myocardial infarction, or repeat revascularization.ResultsA total of 869 patients previously revascularized by percutaneous intervention (83%) or surgery (17%) were recruited. MRF was found in 83.7% (41.1% stent/graft failure, 32.1% progression of coronary disease, and 10.5% residual disease). SR was performed in 70.1%, preferably by percutaneous intervention (95%). The POCE rate at 1 year was 14% in the overall cohort, with 6.4% all‐cause death. In the multivariate analysis, lower POCE rates were found in the groups without MRF (9.4%) and with disease progression (11%) compared with graft/stent failure (17%) and residual disease (18%), hazard ratio 0.67 (95% confidence interval: 0.45–0.99), p = 0.043. At 1 year, the SR group had less chronic persistent angina (19% vs. 34%, p < 0.001), but a higher rate of repeat revascularization (9% vs. 2.9%, p < 0.001).ConclusionMRF was found in 84% of patients with prior revascularization referred for coronary angiography. Stent/graft failure and residual coronary disease were associated with a worse prognosis. SR provided better symptom control at the expense of a higher rate of new revascularization</description><identifier>ISSN: 1522-1946</identifier><identifier>EISSN: 1522-726X</identifier><identifier>DOI: 10.1002/ccd.30804</identifier><language>eng</language><publisher>Washington: Wiley Subscription Services, Inc</publisher><subject>Angina ; Angiography ; Cardiac catheterization ; Graft rejection ; Heart diseases ; Implants ; Medical imaging ; Multivariate analysis ; Myocardial infarction ; Patients ; Prognosis</subject><ispartof>Catheterization and cardiovascular interventions, 2023-10, Vol.102 (4), p.608-619</ispartof><rights>2023 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c250t-73a2c5b5ddc365dfa3b6c1cf0a11931cf8b641cc6630153231ab6e9555108d553</cites><orcidid>0000-0003-4040-4029 ; 0000-0002-1998-3735 ; 0000-0001-7499-1167 ; 0000-0002-2311-4129 ; 0000-0003-4823-5020 ; 0000-0001-7383-6835</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27931,27932</link.rule.ids></links><search><creatorcontrib>Salinas, Pablo</creatorcontrib><creatorcontrib>García‐Camarero, Tamara</creatorcontrib><creatorcontrib>Jimenez‐Kockar, Marcelo</creatorcontrib><creatorcontrib>Regueiro, Ander</creatorcontrib><creatorcontrib>García‐Blas, Sergio</creatorcontrib><creatorcontrib>Gomez‐Menchero, Antonio E.</creatorcontrib><creatorcontrib>Ojeda, Soledad</creatorcontrib><creatorcontrib>Vilchez‐Tschischke, Jean Paul</creatorcontrib><creatorcontrib>Amat‐Santos, Ignacio</creatorcontrib><creatorcontrib>Díez‐Gil, Jose Luis</creatorcontrib><creatorcontrib>Rondán, Juan</creatorcontrib><creatorcontrib>Lozano Ruiz‐Poveda, Fernando</creatorcontrib><creatorcontrib>de Miguel Castro, Antonio</creatorcontrib><creatorcontrib>Manzano, Maria C.</creatorcontrib><creatorcontrib>Pascual‐Tejerina, Virginia</creatorcontrib><creatorcontrib>Cruz‐González, Ignacio</creatorcontrib><creatorcontrib>García Perez‐Velasco, Javier</creatorcontrib><creatorcontrib>Fernández‐Diaz, Jose A.</creatorcontrib><creatorcontrib>Escaned, Javier</creatorcontrib><creatorcontrib>REVASEC working group (collaborators)</creatorcontrib><title>Myocardial revascularization failure among patients requiring cardiac catheterization and secondary revascularization in contemporary clinical practice: Results of the REVASEC multicenter registry</title><title>Catheterization and cardiovascular interventions</title><description>BackgroundMyocardial revascularization failure (MRF) and Secondary revascularization (SR) are contemporary interventional cardiology challenges.AimTo investigate the characteristics, management, and prognosis of patients with myocardial revascularization failure (MRF) and need for secondary revascularization (SR) in contemporary practice.MethodsThe REVASEC study is a prospective registry (NCT03349385), which recruited patients with prior revascularization referred for coronary angiography at 19 centers. The primary endpoint is a patient‐oriented composite (POCE) at 1 year, including death, myocardial infarction, or repeat revascularization.ResultsA total of 869 patients previously revascularized by percutaneous intervention (83%) or surgery (17%) were recruited. MRF was found in 83.7% (41.1% stent/graft failure, 32.1% progression of coronary disease, and 10.5% residual disease). SR was performed in 70.1%, preferably by percutaneous intervention (95%). The POCE rate at 1 year was 14% in the overall cohort, with 6.4% all‐cause death. In the multivariate analysis, lower POCE rates were found in the groups without MRF (9.4%) and with disease progression (11%) compared with graft/stent failure (17%) and residual disease (18%), hazard ratio 0.67 (95% confidence interval: 0.45–0.99), p = 0.043. At 1 year, the SR group had less chronic persistent angina (19% vs. 34%, p < 0.001), but a higher rate of repeat revascularization (9% vs. 2.9%, p < 0.001).ConclusionMRF was found in 84% of patients with prior revascularization referred for coronary angiography. Stent/graft failure and residual coronary disease were associated with a worse prognosis. SR provided better symptom control at the expense of a higher rate of new revascularization</description><subject>Angina</subject><subject>Angiography</subject><subject>Cardiac catheterization</subject><subject>Graft rejection</subject><subject>Heart diseases</subject><subject>Implants</subject><subject>Medical imaging</subject><subject>Multivariate analysis</subject><subject>Myocardial infarction</subject><subject>Patients</subject><subject>Prognosis</subject><issn>1522-1946</issn><issn>1522-726X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNptkU1LAzEQhhdRUKsH_0HAix5a89Gku95KqR-gCH7hbUlns5qym6xJVqi_zx_maMWDeJph5nnfDHmz7IDREaOUnwBUI0FzOt7IdpjkfDjh6mnzp2fFWG1nuzEuKaWF4sVO9nG98qBDZXVDgnnTEfpGB_uuk_WO1No2fTBEt949kw6HxqWI4Gtvg8XRWgpY04tJ5leoXUWiAe8qHVb_GFtHcJlM2_nwRUBjnQW8oQsakgVzSm5N7Bt8zNcEvcnt_HF6N5-RFoe4R21A32cbU1jtZVu1bqLZ_6mD7OFsfj-7GF7dnF_OpldD4JKm4URoDnIhqwqEklWtxUIBg5pqxgqBTb5QYwaglKBMCi6YXihTSCkZzSspxSA7Wvt2wb_2JqaytRFM02hnfB9LnkuWTyiVDNHDP-jS98HhdUhhJiznY4XU8ZqC4GMMpi67YFv8kJLR8ivPEvMsv_MUn1B1mNs</recordid><startdate>20231001</startdate><enddate>20231001</enddate><creator>Salinas, Pablo</creator><creator>García‐Camarero, Tamara</creator><creator>Jimenez‐Kockar, Marcelo</creator><creator>Regueiro, Ander</creator><creator>García‐Blas, Sergio</creator><creator>Gomez‐Menchero, Antonio E.</creator><creator>Ojeda, Soledad</creator><creator>Vilchez‐Tschischke, Jean Paul</creator><creator>Amat‐Santos, Ignacio</creator><creator>Díez‐Gil, Jose Luis</creator><creator>Rondán, Juan</creator><creator>Lozano Ruiz‐Poveda, Fernando</creator><creator>de Miguel Castro, Antonio</creator><creator>Manzano, Maria C.</creator><creator>Pascual‐Tejerina, Virginia</creator><creator>Cruz‐González, Ignacio</creator><creator>García Perez‐Velasco, Javier</creator><creator>Fernández‐Diaz, Jose A.</creator><creator>Escaned, Javier</creator><general>Wiley Subscription Services, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4040-4029</orcidid><orcidid>https://orcid.org/0000-0002-1998-3735</orcidid><orcidid>https://orcid.org/0000-0001-7499-1167</orcidid><orcidid>https://orcid.org/0000-0002-2311-4129</orcidid><orcidid>https://orcid.org/0000-0003-4823-5020</orcidid><orcidid>https://orcid.org/0000-0001-7383-6835</orcidid></search><sort><creationdate>20231001</creationdate><title>Myocardial revascularization failure among patients requiring cardiac catheterization and secondary revascularization in contemporary clinical practice: Results of the REVASEC multicenter registry</title><author>Salinas, Pablo ; García‐Camarero, Tamara ; Jimenez‐Kockar, Marcelo ; Regueiro, Ander ; García‐Blas, Sergio ; Gomez‐Menchero, Antonio E. ; Ojeda, Soledad ; Vilchez‐Tschischke, Jean Paul ; Amat‐Santos, Ignacio ; Díez‐Gil, Jose Luis ; Rondán, Juan ; Lozano Ruiz‐Poveda, Fernando ; de Miguel Castro, Antonio ; Manzano, Maria C. ; Pascual‐Tejerina, Virginia ; Cruz‐González, Ignacio ; García Perez‐Velasco, Javier ; Fernández‐Diaz, Jose A. ; Escaned, Javier</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c250t-73a2c5b5ddc365dfa3b6c1cf0a11931cf8b641cc6630153231ab6e9555108d553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Angina</topic><topic>Angiography</topic><topic>Cardiac catheterization</topic><topic>Graft rejection</topic><topic>Heart diseases</topic><topic>Implants</topic><topic>Medical imaging</topic><topic>Multivariate analysis</topic><topic>Myocardial infarction</topic><topic>Patients</topic><topic>Prognosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Salinas, Pablo</creatorcontrib><creatorcontrib>García‐Camarero, Tamara</creatorcontrib><creatorcontrib>Jimenez‐Kockar, Marcelo</creatorcontrib><creatorcontrib>Regueiro, Ander</creatorcontrib><creatorcontrib>García‐Blas, Sergio</creatorcontrib><creatorcontrib>Gomez‐Menchero, Antonio E.</creatorcontrib><creatorcontrib>Ojeda, Soledad</creatorcontrib><creatorcontrib>Vilchez‐Tschischke, Jean Paul</creatorcontrib><creatorcontrib>Amat‐Santos, Ignacio</creatorcontrib><creatorcontrib>Díez‐Gil, Jose Luis</creatorcontrib><creatorcontrib>Rondán, Juan</creatorcontrib><creatorcontrib>Lozano Ruiz‐Poveda, Fernando</creatorcontrib><creatorcontrib>de Miguel Castro, Antonio</creatorcontrib><creatorcontrib>Manzano, Maria C.</creatorcontrib><creatorcontrib>Pascual‐Tejerina, Virginia</creatorcontrib><creatorcontrib>Cruz‐González, Ignacio</creatorcontrib><creatorcontrib>García Perez‐Velasco, Javier</creatorcontrib><creatorcontrib>Fernández‐Diaz, Jose A.</creatorcontrib><creatorcontrib>Escaned, Javier</creatorcontrib><creatorcontrib>REVASEC working group (collaborators)</creatorcontrib><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Catheterization and cardiovascular interventions</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Salinas, Pablo</au><au>García‐Camarero, Tamara</au><au>Jimenez‐Kockar, Marcelo</au><au>Regueiro, Ander</au><au>García‐Blas, Sergio</au><au>Gomez‐Menchero, Antonio E.</au><au>Ojeda, Soledad</au><au>Vilchez‐Tschischke, Jean Paul</au><au>Amat‐Santos, Ignacio</au><au>Díez‐Gil, Jose Luis</au><au>Rondán, Juan</au><au>Lozano Ruiz‐Poveda, Fernando</au><au>de Miguel Castro, Antonio</au><au>Manzano, Maria C.</au><au>Pascual‐Tejerina, Virginia</au><au>Cruz‐González, Ignacio</au><au>García Perez‐Velasco, Javier</au><au>Fernández‐Diaz, Jose A.</au><au>Escaned, Javier</au><aucorp>REVASEC working group (collaborators)</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Myocardial revascularization failure among patients requiring cardiac catheterization and secondary revascularization in contemporary clinical practice: Results of the REVASEC multicenter registry</atitle><jtitle>Catheterization and cardiovascular interventions</jtitle><date>2023-10-01</date><risdate>2023</risdate><volume>102</volume><issue>4</issue><spage>608</spage><epage>619</epage><pages>608-619</pages><issn>1522-1946</issn><eissn>1522-726X</eissn><abstract>BackgroundMyocardial revascularization failure (MRF) and Secondary revascularization (SR) are contemporary interventional cardiology challenges.AimTo investigate the characteristics, management, and prognosis of patients with myocardial revascularization failure (MRF) and need for secondary revascularization (SR) in contemporary practice.MethodsThe REVASEC study is a prospective registry (NCT03349385), which recruited patients with prior revascularization referred for coronary angiography at 19 centers. The primary endpoint is a patient‐oriented composite (POCE) at 1 year, including death, myocardial infarction, or repeat revascularization.ResultsA total of 869 patients previously revascularized by percutaneous intervention (83%) or surgery (17%) were recruited. MRF was found in 83.7% (41.1% stent/graft failure, 32.1% progression of coronary disease, and 10.5% residual disease). SR was performed in 70.1%, preferably by percutaneous intervention (95%). The POCE rate at 1 year was 14% in the overall cohort, with 6.4% all‐cause death. In the multivariate analysis, lower POCE rates were found in the groups without MRF (9.4%) and with disease progression (11%) compared with graft/stent failure (17%) and residual disease (18%), hazard ratio 0.67 (95% confidence interval: 0.45–0.99), p = 0.043. At 1 year, the SR group had less chronic persistent angina (19% vs. 34%, p < 0.001), but a higher rate of repeat revascularization (9% vs. 2.9%, p < 0.001).ConclusionMRF was found in 84% of patients with prior revascularization referred for coronary angiography. Stent/graft failure and residual coronary disease were associated with a worse prognosis. SR provided better symptom control at the expense of a higher rate of new revascularization</abstract><cop>Washington</cop><pub>Wiley Subscription Services, Inc</pub><doi>10.1002/ccd.30804</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0003-4040-4029</orcidid><orcidid>https://orcid.org/0000-0002-1998-3735</orcidid><orcidid>https://orcid.org/0000-0001-7499-1167</orcidid><orcidid>https://orcid.org/0000-0002-2311-4129</orcidid><orcidid>https://orcid.org/0000-0003-4823-5020</orcidid><orcidid>https://orcid.org/0000-0001-7383-6835</orcidid></addata></record> |
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| subjects | Angina Angiography Cardiac catheterization Graft rejection Heart diseases Implants Medical imaging Multivariate analysis Myocardial infarction Patients Prognosis |
| title | Myocardial revascularization failure among patients requiring cardiac catheterization and secondary revascularization in contemporary clinical practice: Results of the REVASEC multicenter registry |
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