Exploring Photoswitchable Binding Interactions with Small‐Molecule‐ and Peptide‐Based Inhibitors of Trypsin

The ability to photochemically activate a drug, both when and where needed, requires optimisation of the difference in biological activity between each isomeric state. As a step to this goal, we report small‐molecule‐ and peptide‐based inhibitors of the same protease—trypsin—to better understand how...

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Veröffentlicht in:Chembiochem : a European journal of chemical biology 2023-10, Vol.24 (20), p.e202300453-n/a
Hauptverfasser: Palasis, Kathryn A., Peddie, Victoria, Turner, Dion J. L., Zhang, Xiaozhou, Yu, Jingxian, Abell, Andrew D.
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Sprache:eng
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