Cartilage-inspired terpolymer hydrogel with excellent mechanical properties and superior lubricating ability
Osteoarthritis (OA), the most common degenerative joint disorder, seriously affects patients' daily activities. Recently, hydrogels, due to their similar structure to articular cartilage, have shown great potential as cartilage-repairing materials. In the present work, we developed a simple pro...
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| Veröffentlicht in: | Soft matter 2023-08, Vol.19 (33), p.6341-6354 |
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| creator | Wang, Binbin Li, Ziheng Li, Shuangjian Xv, Qihang You, Deqiang Tu, Xiaohui Li, Wei Wang, Xiaojian |
| description | Osteoarthritis (OA), the most common degenerative joint disorder, seriously affects patients' daily activities. Recently, hydrogels, due to their similar structure to articular cartilage, have shown great potential as cartilage-repairing materials. In the present work, we developed a simple process for fabricating terpolymer [P(acrylamide-
co
-acrylic acid-
co
-2-acrylamido-2-methyl-1-propanesulfonic acid)/Fe
3+
] hydrogel [P(AAm-
co
-AAc-
co
-AMPS)/Fe
3+
]. The content of AMPS was found to show a crucial effect on the mechanical and tribological performance of the terpolymer hydrogel. When the content of AMPS was 0.45 mol L
−1
, the compressive strength, modulus, and friction coefficient of the terpolymer hydrogel were 66.60 ± 1.79 MPa, 2.10 ± 0.16 MPa, and 0.032, respectively. In addition, the hydrogel showed high wear durability and the friction coefficient was as low as 0.038 after 3.6 × 10
5
sliding cycles.
For the treatment of osteoarthritis, terpolymer hydrogels with excellent mechanical properties, superior tribological performance and long-term lubricity were prepared. |
| doi_str_mv | 10.1039/d3sm00841j |
| format | Article |
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co
-acrylic acid-
co
-2-acrylamido-2-methyl-1-propanesulfonic acid)/Fe
3+
] hydrogel [P(AAm-
co
-AAc-
co
-AMPS)/Fe
3+
]. The content of AMPS was found to show a crucial effect on the mechanical and tribological performance of the terpolymer hydrogel. When the content of AMPS was 0.45 mol L
−1
, the compressive strength, modulus, and friction coefficient of the terpolymer hydrogel were 66.60 ± 1.79 MPa, 2.10 ± 0.16 MPa, and 0.032, respectively. In addition, the hydrogel showed high wear durability and the friction coefficient was as low as 0.038 after 3.6 × 10
5
sliding cycles.
For the treatment of osteoarthritis, terpolymer hydrogels with excellent mechanical properties, superior tribological performance and long-term lubricity were prepared.</description><identifier>ISSN: 1744-683X</identifier><identifier>EISSN: 1744-6848</identifier><identifier>DOI: 10.1039/d3sm00841j</identifier><identifier>PMID: 37575029</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Acrylamide ; Acrylic acid ; Cartilage ; Cartilage (articular) ; Cartilage diseases ; Coefficient of friction ; Compressive strength ; Durability ; Friction ; Hydrogels ; Iron ; Mechanical properties ; Osteoarthritis ; Terpolymers ; Tribology</subject><ispartof>Soft matter, 2023-08, Vol.19 (33), p.6341-6354</ispartof><rights>Copyright Royal Society of Chemistry 2023</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c296t-4f7419752dea96b175c6fc59fd0da53d64b00cf98c04424f2bb46f2de0a5c5573</cites><orcidid>0000-0003-3205-1999</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37575029$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Binbin</creatorcontrib><creatorcontrib>Li, Ziheng</creatorcontrib><creatorcontrib>Li, Shuangjian</creatorcontrib><creatorcontrib>Xv, Qihang</creatorcontrib><creatorcontrib>You, Deqiang</creatorcontrib><creatorcontrib>Tu, Xiaohui</creatorcontrib><creatorcontrib>Li, Wei</creatorcontrib><creatorcontrib>Wang, Xiaojian</creatorcontrib><title>Cartilage-inspired terpolymer hydrogel with excellent mechanical properties and superior lubricating ability</title><title>Soft matter</title><addtitle>Soft Matter</addtitle><description>Osteoarthritis (OA), the most common degenerative joint disorder, seriously affects patients' daily activities. Recently, hydrogels, due to their similar structure to articular cartilage, have shown great potential as cartilage-repairing materials. In the present work, we developed a simple process for fabricating terpolymer [P(acrylamide-
co
-acrylic acid-
co
-2-acrylamido-2-methyl-1-propanesulfonic acid)/Fe
3+
] hydrogel [P(AAm-
co
-AAc-
co
-AMPS)/Fe
3+
]. The content of AMPS was found to show a crucial effect on the mechanical and tribological performance of the terpolymer hydrogel. When the content of AMPS was 0.45 mol L
−1
, the compressive strength, modulus, and friction coefficient of the terpolymer hydrogel were 66.60 ± 1.79 MPa, 2.10 ± 0.16 MPa, and 0.032, respectively. In addition, the hydrogel showed high wear durability and the friction coefficient was as low as 0.038 after 3.6 × 10
5
sliding cycles.
For the treatment of osteoarthritis, terpolymer hydrogels with excellent mechanical properties, superior tribological performance and long-term lubricity were prepared.</description><subject>Acrylamide</subject><subject>Acrylic acid</subject><subject>Cartilage</subject><subject>Cartilage (articular)</subject><subject>Cartilage diseases</subject><subject>Coefficient of friction</subject><subject>Compressive strength</subject><subject>Durability</subject><subject>Friction</subject><subject>Hydrogels</subject><subject>Iron</subject><subject>Mechanical properties</subject><subject>Osteoarthritis</subject><subject>Terpolymers</subject><subject>Tribology</subject><issn>1744-683X</issn><issn>1744-6848</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNpd0c1L5DAYBvAgirquF-9KwMuyUDdpkqY5yuyXonhwF7yVNHk7kyH9MGnR-e_NODqCpyTkx8vD-yB0QskFJUz9sCy2hJScLnfQIZWcZ0XJy93tnT0coC8xLglhCRX76IBJIQXJ1SHyMx1G5_UcMtfFwQWweIQw9H7VQsCLlQ39HDx-cuMCw7MB76EbcQtmoTtntMdD6AdIMyBi3Vkcp_RyfcB-qkMCo-vmWNfOu3H1Fe012kc4fjuP0P_fv_7N_mY3d3-uZpc3mclVMWa8kZwqKXILWhU1lcIUjRGqscRqwWzBa0JMo0pDOM95k9c1L5qkiRZGCMmO0LfN3JTtcYI4Vq2L6-i6g36KVV4KImmp5Jqef6LLfgpdSrdWXBFeUJbU940yoY8xQFMNwbU6rCpKqnUH1U92f_vawXXCZ28jp7oFu6XvS0_gdANCNNvfjxLZC-mHjeA</recordid><startdate>20230823</startdate><enddate>20230823</enddate><creator>Wang, Binbin</creator><creator>Li, Ziheng</creator><creator>Li, Shuangjian</creator><creator>Xv, Qihang</creator><creator>You, Deqiang</creator><creator>Tu, Xiaohui</creator><creator>Li, Wei</creator><creator>Wang, Xiaojian</creator><general>Royal Society of Chemistry</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3205-1999</orcidid></search><sort><creationdate>20230823</creationdate><title>Cartilage-inspired terpolymer hydrogel with excellent mechanical properties and superior lubricating ability</title><author>Wang, Binbin ; Li, Ziheng ; Li, Shuangjian ; Xv, Qihang ; You, Deqiang ; Tu, Xiaohui ; Li, Wei ; Wang, Xiaojian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c296t-4f7419752dea96b175c6fc59fd0da53d64b00cf98c04424f2bb46f2de0a5c5573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Acrylamide</topic><topic>Acrylic acid</topic><topic>Cartilage</topic><topic>Cartilage (articular)</topic><topic>Cartilage diseases</topic><topic>Coefficient of friction</topic><topic>Compressive strength</topic><topic>Durability</topic><topic>Friction</topic><topic>Hydrogels</topic><topic>Iron</topic><topic>Mechanical properties</topic><topic>Osteoarthritis</topic><topic>Terpolymers</topic><topic>Tribology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Binbin</creatorcontrib><creatorcontrib>Li, Ziheng</creatorcontrib><creatorcontrib>Li, Shuangjian</creatorcontrib><creatorcontrib>Xv, Qihang</creatorcontrib><creatorcontrib>You, Deqiang</creatorcontrib><creatorcontrib>Tu, Xiaohui</creatorcontrib><creatorcontrib>Li, Wei</creatorcontrib><creatorcontrib>Wang, Xiaojian</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Soft matter</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Binbin</au><au>Li, Ziheng</au><au>Li, Shuangjian</au><au>Xv, Qihang</au><au>You, Deqiang</au><au>Tu, Xiaohui</au><au>Li, Wei</au><au>Wang, Xiaojian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cartilage-inspired terpolymer hydrogel with excellent mechanical properties and superior lubricating ability</atitle><jtitle>Soft matter</jtitle><addtitle>Soft Matter</addtitle><date>2023-08-23</date><risdate>2023</risdate><volume>19</volume><issue>33</issue><spage>6341</spage><epage>6354</epage><pages>6341-6354</pages><issn>1744-683X</issn><eissn>1744-6848</eissn><abstract>Osteoarthritis (OA), the most common degenerative joint disorder, seriously affects patients' daily activities. Recently, hydrogels, due to their similar structure to articular cartilage, have shown great potential as cartilage-repairing materials. In the present work, we developed a simple process for fabricating terpolymer [P(acrylamide-
co
-acrylic acid-
co
-2-acrylamido-2-methyl-1-propanesulfonic acid)/Fe
3+
] hydrogel [P(AAm-
co
-AAc-
co
-AMPS)/Fe
3+
]. The content of AMPS was found to show a crucial effect on the mechanical and tribological performance of the terpolymer hydrogel. When the content of AMPS was 0.45 mol L
−1
, the compressive strength, modulus, and friction coefficient of the terpolymer hydrogel were 66.60 ± 1.79 MPa, 2.10 ± 0.16 MPa, and 0.032, respectively. In addition, the hydrogel showed high wear durability and the friction coefficient was as low as 0.038 after 3.6 × 10
5
sliding cycles.
For the treatment of osteoarthritis, terpolymer hydrogels with excellent mechanical properties, superior tribological performance and long-term lubricity were prepared.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>37575029</pmid><doi>10.1039/d3sm00841j</doi><tpages>14</tpages><orcidid>https://orcid.org/0000-0003-3205-1999</orcidid></addata></record> |
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| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Acrylamide Acrylic acid Cartilage Cartilage (articular) Cartilage diseases Coefficient of friction Compressive strength Durability Friction Hydrogels Iron Mechanical properties Osteoarthritis Terpolymers Tribology |
| title | Cartilage-inspired terpolymer hydrogel with excellent mechanical properties and superior lubricating ability |
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