Semi-synthetic human albumin isoforms: Production, structure, binding capacities and influence on a routine laboratory test

Human Serum Albumin (HSA) undergoes Post-Translational-Modifications (PTMs) leading to isoforms affecting its oncotic and non-oncotic properties. HSA is comprised of several isoforms whose abundance may vary with pathologies such as diabetes, kidney and liver diseases. Studying their impact separate...

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Veröffentlicht in:	International journal of biological macromolecules 2023-10, Vol.250, p.126239-126239, Article 126239
Hauptverfasser:	Lakis, Roy, Sauvage, François-Ludovic, Pinault, Emilie, Marquet, Pierre, Saint-Marcoux, Franck, El Balkhi, Souleiman
Format:	Artikel
Sprache:	eng
Schlagworte:	antioxidants biomarkers Bottom-up diabetes HSA isoforms Human serum albumin humans ICP-MS kidneys laboratory experimentation ligands liver mass spectrometry oxidation pathogenicity Post-translational-modification Top-down
Online-Zugang:	Volltext
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