Jiawei-Xiaoyao pill elicits a rapid antidepressant effect, dependent on activating CaMKII/mTOR/BDNF signaling pathway in the hippocampus

Jiawei-Xiaoyao pill (JWX), a traditional Chinese medicine, was recorded in ancient Chinese medicine pharmacopoeia using for treatment of various diseases, including mood disorders. Current mainstream antidepressants have a disadvantage in delayed onset of action. The rapid antidepressant potential o...

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Veröffentlicht in:	Journal of ethnopharmacology 2024-01, Vol.318, p.117016-117016, Article 117016
Hauptverfasser:	Zhang, Hailou, Sun, Yan, Huang, Zihao, Wu, Zhangjie, Ying, Yin, Liu, Ruiyi, Lin, Juan, Li, Chuyuan, Chen, Gang
Format:	Artikel
Sprache:	eng
Schlagworte:	antagonists antidepressants BDNF calcium-calmodulin-dependent protein kinase CaMKII corticosterone emotions Hippocampus immunoblotting Jiawei-Xiaoyao pill Ketamine neuroplasticity Oriental traditional medicine phosphorylation rapamycin Rapid antidepressant
Online-Zugang:	Volltext
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