An implication of the mitochondrial carrier SLC25A3 as an oxidative stress modulator in NAFLD

Nonalcoholic fatty liver disease (NAFLD) is a type of steatosis not associated with excessive alcohol intake and includes nonalcoholic steatohepatitis (NASH), which can progress to advanced fibrosis and hepatocellular carcinoma. Mitochondrial dysfunction causes oxidative stress, triggering hepatocyt...

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Veröffentlicht in:	Experimental cell research 2023-10, Vol.431 (1), p.113740-113740, Article 113740
Hauptverfasser:	Nakanishi, Takeo, Kawasaki, Yuki, Nakamura, Yoshinobu, Kimura, Yuuki, Kawamura, Kotone, Shumba, Melody N., Shimokawa, Noriaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Copper transport Fatty acid metabolism Lipid Liver injury Mitochondrial carriers Mitochondrial membrane potential Oxidative stress Phosphate carrier Redox regulation SLC25A family
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