Platelet-targeted gene therapy induces immune tolerance in hemophilia and beyond

Blood platelets have unique storage and delivery capabilities. Platelets play fundamental roles in hemostasis, inflammatory reactions, and immune responses. Beyond their functions, platelets have been used as a target for gene therapy. Platelet-targeted gene therapy aims to deliver a sustained expre...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2024-01, Vol.22 (1), p.23-34
Hauptverfasser:	Kumar, Saurabh, Schroeder, Jocelyn A, Shi, Qizhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Platelets - metabolism Factor VIII - metabolism Genetic Therapy - methods Hemophilia A - genetics Hemophilia A - therapy Hemostasis Humans Immune Tolerance
Online-Zugang:	Volltext
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