Periplocoside P affects synaptic transmission at the neuromuscular junction and reduces synaptic excitability in Drosophila melanogaster by inhibiting V‐ATPase

BACKGROUND Periplocoside P (PSP) is a major component of Periploca sepium Bunge known for its potent insecticidal activity. V‐Type adenosine triphosphatase (V‐ATPase), which is widely distributed in the cytoplasmic membranes and organelles of eukaryotic cells, plays a crucial role in synaptic excita...

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