Quantitative increases of extracellular vesicles in prolonged cold storage of platelets increases the potential to enhance fibrin clot formation

Background Platelet derived extracellular vesicles (EVs) display a pro‐coagulant phenotype and are generated throughout platelet concentrate (PC) storage. Cold storage (CS) of PCs is thought to provide a superior haemostatic advantage over room temperature (RT) storage and could prolong the storage...

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Veröffentlicht in:	Transfusion medicine (Oxford, England) England), 2023-12, Vol.33 (6), p.467-477
Hauptverfasser:	Nash, J., Davies, A., Saunders, C. V., George, C. E., Williams, J. O., James, P. E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Coagulation Blood Platelets Blood Preservation buffy‐coat derived platelet concentrates cold storage Cryopreservation Extracellular Vesicles Fibrin Humans platelet transfusion
Online-Zugang:	Volltext
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