Therapeutic applications of local injection of hsa-miR-634 into canine spontaneous malignant melanoma tumors

Malignant melanoma (MM) is one of the most common tumors in both dogs and humans. As canine MM (CMM) and human MM (HMM) have similar clinical characteristics, CMM appears to be a good clinical model for HMM. We previously demonstrated that the introduction of a synthetic double-strand-microRNA-634 (...

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Veröffentlicht in:	Cancer gene therapy 2023-11, Vol.30 (11), p.1524-1529
Hauptverfasser:	Yoshikawa, Ryutaro, Inoue, Jun, Iwasaki, Ryota, Terauchi, Mitsuhiko, Fujii, Yuji, Ohta, Maya, Hasegawa, Tomomi, Mizuno, Rui, Mori, Takashi, Inazawa, Johji
Format:	Artikel
Sprache:	eng
Schlagworte:	13/89 631/208/191/505 631/67/1665 631/67/70 96/2 Animals Antitumor activity Apoptosis Biomedical and Life Sciences Biomedicine Cell death Cell Line, Tumor Cell Proliferation - genetics Dogs Gene Expression Gene Expression Regulation, Neoplastic Gene Therapy Humans Medical treatment Melanoma Melanoma - drug therapy Melanoma - genetics Melanoma, Cutaneous Malignant Metastases MicroRNAs - genetics MicroRNAs - metabolism miRNA Skin cancer Survivin Therapeutic applications Tumor cell lines Tumors
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