First Known Human Death After Infection With the Avian Influenza A/H3N8 Virus: Guangdong Province, China, March 2023

First Known Human Death After Infection With the Avian Influenza A/H3N8 Virus: Guangdong Province, China, March 2023

Abstract Here, we report on a case of human infection with the H3N8 avian influenza virus. The patient had multiple myeloma and died of severe infection. Genome analysis showed multiple gene mutations and reassortments without mammalian-adaptive mutations. This suggests that avian influenza (A/H3N8)...

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Veröffentlicht in:Clinical infectious diseases 2024-03, Vol.78 (3), p.646-650
Hauptverfasser: Zhuang, Yali, Wang, Man, Liang, Lijun, Mao, Yunxia, Wang, Kaibin, Yang, Shuhuan, Deng, Aiping, Zeng, Kewen, Zhang, Yingtao, Zhang, Guanting, Kang, Min, Li, Baisheng, Zhang, Meng, Ye, Shinan
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Sprache:eng
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Zusammenfassung:Abstract Here, we report on a case of human infection with the H3N8 avian influenza virus. The patient had multiple myeloma and died of severe infection. Genome analysis showed multiple gene mutations and reassortments without mammalian-adaptive mutations. This suggests that avian influenza (A/H3N8) virus infection could be lethal for immunocompromised persons. Graphical Abstract Graphical Abstract This graphical abstract is also available at Tidbit: https://tidbitapp.io/tidbits/the-first-known-human-death-after-infection-with-the-avian-influenza-a-h3n8-virus-guangdong-province-china-march-2023-dda3f33c-07ea-4aa4-a5e9-f9c318546651
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciad462