Medicinal chemistry approaches for the discovery of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors as antimalarial agents
Malaria is a severe human disease and a global health problem because of drug-resistant strains. Drugs reported to prevent the growth of parasites target various phases of the parasites' life cycle. Antimalarial drugs can inhibit key enzymes that are responsible for the cellular growth and deve...
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| Veröffentlicht in: | Future medicinal chemistry 2023-07, Vol.15 (14), p.1295-1321 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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