TissueGene-C induces long-term analgesic effects through regulation of pain mediators and neuronal sensitization in a rat monoiodoacetate-induced model of osteoarthritis pain

TissueGene-C (TG-C), a combination of human allogeneic chondrocytes and irradiated GP2-293 cells engineered to overexpress transforming growth factor-β1 (TGF-β1), has been developed as a novel cell-based gene therapy and a candidate for disease modifying osteoarthritis drug (DMOAD). We aim to invest...

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Veröffentlicht in:	Osteoarthritis and cartilage 2023-12, Vol.31 (12), p.1567-1580
Hauptverfasser:	Park, Eui Ho, Seo, Jinwon, Lee, Yunsin, Park, Kiwon, Kim, Kyoung-Ran, Kim, Sujeong, Mobasheri, Ali, Choi, Heonsik
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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