A novel small molecule inhibitor of p38⍺ MAP kinase augments cardiomyocyte cell cycle entry in response to direct cell cycle stimulation

Background and Purpose Myocardial infarction (MI) is the leading cause of mortality globally due in part to the limited ability of cardiomyocytes (CMs) to regenerate. Recently, we demonstrated that overexpression of four‐cell cycle factors, CDK1, CDK4, cyclin B1 and cyclin D1 (4F), induced cell divi...

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