Ameliorative effects of silybin against avermectin-triggered carp spleen mitochondrial dysfunction and apoptosis through inhibition of PERK-ATF4-CHOP signaling pathway

The aim of this study was to investigate the splenic tissue damage of environmental biological drug avermectin to freshwater cultured carp and to evaluate the effect of silybin on the splenic tissue damage of carp induced by avermectin. A total of 60 carp were divided into 4 groups with 15 carp in e...

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Veröffentlicht in:	Fish physiology and biochemistry 2023-10, Vol.49 (5), p.895-910
Hauptverfasser:	Pan, En-Zhuang, Xin, Yue, Li, Xue-Qing, Wu, Xin-Yu, Tan, Xue-Lian, Dong, Jing-Quan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Animal Biochemistry Animal Physiology Apoptosis ATP Avermectin Basic diets Biochemical tests Biological activity Biomedical and Life Sciences Carp Damage Detection Diet Endoplasmic reticulum Exposure Feed additives Freshwater Freshwater & Marine Ecology Freshwater fish Freshwater fishes Histology Immunohistochemistry Inland water environment Life Sciences Membrane potential Membranes Mitochondria Morphology Oxidative stress Pesticides Pollution Signal transduction Spleen Staining Tissue Tissues Water purification Zoology
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