Platycodin D induces apoptotic cell death through PI3K/AKT and MAPK/ERK pathways and synergizes with venetoclax in acute myeloid leukemia

Acute myeloid leukemia (AML) is a highly heterogeneous and rapidly progressive hematopoietic neoplasm characterized by frequent relapses and variable prognoses. The development of new treatment options, therefore, is of crucial importance. Platycodin D (PD) is a triterpenoid saponin, extracted from...

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Veröffentlicht in:	European journal of pharmacology 2023-10, Vol.956, p.175957-175957, Article 175957
Hauptverfasser:	Jiang, Xia, Lin, Ye, Zhao, Mengting, Li, Youhong, Ye, Peipei, Pei, Renzhi, Lu, Ying, Jiang, Lei
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Apoptosis Platycodin D Venetoclax
Online-Zugang:	Volltext
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