Ferritin-nanocaged copper arsenite minerals with oxidative stress-amplifying activity for targeted cancer therapy

We report copper(II) arsenite-encapsulated ferritin nanoparticles (CuAS-FNs) as oxidative stress-amplifying anticancer agents. The CuAS-FNs were fabricated through CuAS mineralization in the cavity of the FNs. The formation of crystalline CuAS complex minerals in the FNs was systematically identifie...

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Veröffentlicht in:	Journal of controlled release 2023-09, Vol.361, p.350-360
Hauptverfasser:	Lee, Kyung Kwan, Kim, Jong-Won, Lee, Chang-Soo, Lee, Sang Cheon
Format:	Artikel
Sprache:	eng
Schlagworte:	Arsenite Cancer therapy Fenton reaction Ferritin Oxidative stress Reactive oxygen species
Online-Zugang:	Volltext
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