Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus

Human ribonuclease (RNase) 1 and bovine RNase A are the proto-types of the secretory “pancreatic-type” (pt)-RNase super-family. RNase A can oligomerize through the 3D domain swapping (DS) mechanism upon acetic acid (HAc) lyophilisation, producing enzymatically active oligomeric conformers by swappin...

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Veröffentlicht in:	International journal of biological macromolecules 2023-09, Vol.249, p.126110-126110, Article 126110
Hauptverfasser:	Noro, Irene, Bettin, Ilaria, Fasoli, Sabrina, Smania, Marcello, Lunardi, Luca, Giannini, Michele, Andreoni, Leonardo, Montioli, Riccardo, Gotte, Giovanni
Format:	Artikel
Sprache:	eng
Schlagworte:	3D domain swapping Enzymatic activity Protein oligomerization Ribonuclease 1
Online-Zugang:	Volltext
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