Ursolic acid alleviates steroid-induced avascular necrosis of the femoral head in mouse by inhibiting apoptosis and rescuing osteogenic differentiation

Steroid-induced avascular necrosis of femoral head (SANFH) is a common disorder worldwide with high disability. Overdose of glucocorticoid (GC) is the most common non-traumatic cause of SANFH. Up until now, there are limited therapeutic strategies for curing SANFH, and the mechanisms underlying SANF...

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Veröffentlicht in:	Toxicology and applied pharmacology 2023-09, Vol.475, p.116649-116649, Article 116649
Hauptverfasser:	Liu, Qian, Wu, Yuyang, Li, Sisi, Yoon, Somy, Zhang, Jiaxin, Wang, Xiaoyi, Hu, Luoshuang, Su, Chenying, Zhang, Chunwu, Wu, Yungang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cell Differentiation Femur Head Necrosis - chemically induced Femur Head Necrosis - drug therapy Femur Head Necrosis - pathology Mice Osteogenesis Steroids Ursolic Acid
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