Absolute Quantification of Dynamic Cellular Uptake of Small Extracellular Vesicles via Lanthanide Element Labeling and ICP–MS

Small extracellular vesicles (sEVs) are increasingly reported to play important roles in numerous physiological and pathological processes. Cellular uptake of sEVs is of great significance for functional regulation in recipient cells. Although various sEV quantification, labeling, and tracking metho...

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Veröffentlicht in:	Analytical chemistry (Washington) 2023-08, Vol.95 (32), p.11934-11942
Hauptverfasser:	Yang, Ningli, Zhao, Chuanping, Kong, Linlin, Zhang, Baoying, Han, Chunguang, Zhang, Yangjun, Qian, Xiaohong, Qin, Weijie
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Chelation Chemistry Endocytosis Europium Extracellular vesicles Inductively coupled plasma mass spectrometry Intracellular signalling Labeling Mass spectrometry Mass spectroscopy Phenotypic variations Stability analysis Structure-function relationships Vesicles
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