Arsenic affects homologous recombination and single-strand annealing but not end-joining pathways during DNA double-strand break repair

Arsenic is a carcinogen that can cause skin, lung, and bladder cancer. While DNA double-strand breaks (DSBs) have been implicated in arsenic-induced carcinogenesis, the exact mechanism remains unclear. In this study, we performed genetic analysis to examine the impact of arsenic trioxide (As O ) on...

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