Microglial and astrocytic responses in the human midcingulate cortex in Huntington's disease

Huntington's disease patients can present with variable difficulties of motor functioning, mood, and cognition. Neurodegeneration occurs in the anterior cingulate cortex of some Huntington's disease patients and is linked to the presentation of mood symptomatology. Neuroinflammation, perpe...

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Veröffentlicht in:	Annals of neurology 2023-11, Vol.94 (5), p.895-910
Hauptverfasser:	Palpagama, Thulani, Mills, Aimee Rose, Ferguson, Mackenzie Wendy, Vikas Ankeal, Praju, Turner, Clinton, Tippett, Lynette, van der Werf, Bert, Waldvogel, Henry John, Faull, Richard Lewis Maxwell, Kwakowsky, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Astrocytes Cognition Connexin 43 Correlation Cortex (cingulate) Density Excitatory amino acid transporter 2 Glial fibrillary acidic protein Glutamic acid transporter Huntingtin Huntington's disease Huntingtons disease Immunohistochemistry Inflammation Microglia Mood Morphology Mutants Neurodegeneration Neuronal-glial interactions Proteins Signs and symptoms
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