ERCP findings provide further justification for a “surgery-first” mindset in choledocholithiasis

Introduction Choledocholithiasis is most often managed in a two-procedure pathway including endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic cholecystectomy (LC). In contrast, a single-stage, surgery-first approach consisting of LC, cholangiogram, and laparoscopic commo...

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Veröffentlicht in:Surgical endoscopy 2023-11, Vol.37 (11), p.8714-8719
Hauptverfasser: Sanin, Gloria, Cambronero, Gabriel, Patterson, James, Bosley, Maggie, Ganapathy, Aravindh, Wescott, Carl, Neff, Lucas
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container_end_page 8719
container_issue 11
container_start_page 8714
container_title Surgical endoscopy
container_volume 37
creator Sanin, Gloria
Cambronero, Gabriel
Patterson, James
Bosley, Maggie
Ganapathy, Aravindh
Wescott, Carl
Neff, Lucas
description Introduction Choledocholithiasis is most often managed in a two-procedure pathway including endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic cholecystectomy (LC). In contrast, a single-stage, surgery-first approach consisting of LC, cholangiogram, and laparoscopic common bile duct exploration (LCBDE) is associated with reduced hospital stays and equivalent morbidity. Despite this, nationwide referral patterns heavily favor ERCP, obscuring those undergoing ERCP with obstructions amenable to simple intraoperative interventions. We hypothesized that most patients had endoscopic findings consistent with simple sludge or small-to-medium stones, which could have been cleared by basic LCBDE maneuvers. Methods We retrospectively reviewed 294 patients > 18 years old who underwent preoperative ERCP for the management of suspected choledocholithiasis. Exclusion criteria included: failed ERCP, cholangitis, prior cholecystectomy, patient refusal of surgery, or medical conditions precluding surgical candidacy. Stone size was categorized as small (0–4 mm), medium (5–7 mm), and large (≥ 8 mm). Results At the time of ERCP, 37 (20.1%) patients had sludge only, 96 (52.2%) had stones only, 42 (22.8%) had sludge and stones, and 9 (4.8%) had no stones. Of the 138 patients with any stones, 37 (26.8%) had small stones, 41 (29.7%) medium, 43 (31.2%) large, and 17 (12.3%) had uncharacterizable stones. Overall, 74.3% of patients had findings of sludge, stones (0–7 mm), or negative ERCP. Conclusion The majority of patients who underwent preoperative ERCP for suspected choledocholithiasis had findings that are amenable to simple intraoperative interventions. In fact, over a quarter of the patients had a negative ERCP, sludge, or small stones which would likely be cleared by flushing/glucagon precluding any further instrumentation. While large stones may require more advanced techniques, this represents a small percentage of patients. Surgery-first management for suspected choledocholithiasis can offer an efficient alternative for the majority of patients.
doi_str_mv 10.1007/s00464-023-10329-x
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In contrast, a single-stage, surgery-first approach consisting of LC, cholangiogram, and laparoscopic common bile duct exploration (LCBDE) is associated with reduced hospital stays and equivalent morbidity. Despite this, nationwide referral patterns heavily favor ERCP, obscuring those undergoing ERCP with obstructions amenable to simple intraoperative interventions. We hypothesized that most patients had endoscopic findings consistent with simple sludge or small-to-medium stones, which could have been cleared by basic LCBDE maneuvers. Methods We retrospectively reviewed 294 patients &gt; 18 years old who underwent preoperative ERCP for the management of suspected choledocholithiasis. Exclusion criteria included: failed ERCP, cholangitis, prior cholecystectomy, patient refusal of surgery, or medical conditions precluding surgical candidacy. Stone size was categorized as small (0–4 mm), medium (5–7 mm), and large (≥ 8 mm). Results At the time of ERCP, 37 (20.1%) patients had sludge only, 96 (52.2%) had stones only, 42 (22.8%) had sludge and stones, and 9 (4.8%) had no stones. Of the 138 patients with any stones, 37 (26.8%) had small stones, 41 (29.7%) medium, 43 (31.2%) large, and 17 (12.3%) had uncharacterizable stones. Overall, 74.3% of patients had findings of sludge, stones (0–7 mm), or negative ERCP. Conclusion The majority of patients who underwent preoperative ERCP for suspected choledocholithiasis had findings that are amenable to simple intraoperative interventions. In fact, over a quarter of the patients had a negative ERCP, sludge, or small stones which would likely be cleared by flushing/glucagon precluding any further instrumentation. While large stones may require more advanced techniques, this represents a small percentage of patients. Surgery-first management for suspected choledocholithiasis can offer an efficient alternative for the majority of patients.</description><identifier>ISSN: 0930-2794</identifier><identifier>EISSN: 1432-2218</identifier><identifier>DOI: 10.1007/s00464-023-10329-x</identifier><identifier>PMID: 37524916</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>2023 SAGES Oral ; Abdominal Surgery ; Adolescent ; Cholangiography - methods ; Cholangiopancreatography, Endoscopic Retrograde - methods ; Cholecystectomy ; Cholecystectomy, Laparoscopic - methods ; Choledocholithiasis - diagnostic imaging ; Choledocholithiasis - surgery ; Endoscopy ; Gastroenterology ; Gynecology ; Hepatology ; Humans ; Laparoscopy ; Medicine ; Medicine &amp; Public Health ; Proctology ; Retrospective Studies ; Sewage ; Sludge ; Surgery</subject><ispartof>Surgical endoscopy, 2023-11, Vol.37 (11), p.8714-8719</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023. 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The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-c14cb93b3bf659f3f9731ec69e792dadd86de5ccb7ed506802e77a85f9c67e033</citedby><cites>FETCH-LOGICAL-c375t-c14cb93b3bf659f3f9731ec69e792dadd86de5ccb7ed506802e77a85f9c67e033</cites><orcidid>0000-0003-0435-1601</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00464-023-10329-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00464-023-10329-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37524916$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sanin, Gloria</creatorcontrib><creatorcontrib>Cambronero, Gabriel</creatorcontrib><creatorcontrib>Patterson, James</creatorcontrib><creatorcontrib>Bosley, Maggie</creatorcontrib><creatorcontrib>Ganapathy, Aravindh</creatorcontrib><creatorcontrib>Wescott, Carl</creatorcontrib><creatorcontrib>Neff, Lucas</creatorcontrib><title>ERCP findings provide further justification for a “surgery-first” mindset in choledocholithiasis</title><title>Surgical endoscopy</title><addtitle>Surg Endosc</addtitle><addtitle>Surg Endosc</addtitle><description>Introduction Choledocholithiasis is most often managed in a two-procedure pathway including endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic cholecystectomy (LC). In contrast, a single-stage, surgery-first approach consisting of LC, cholangiogram, and laparoscopic common bile duct exploration (LCBDE) is associated with reduced hospital stays and equivalent morbidity. Despite this, nationwide referral patterns heavily favor ERCP, obscuring those undergoing ERCP with obstructions amenable to simple intraoperative interventions. We hypothesized that most patients had endoscopic findings consistent with simple sludge or small-to-medium stones, which could have been cleared by basic LCBDE maneuvers. Methods We retrospectively reviewed 294 patients &gt; 18 years old who underwent preoperative ERCP for the management of suspected choledocholithiasis. Exclusion criteria included: failed ERCP, cholangitis, prior cholecystectomy, patient refusal of surgery, or medical conditions precluding surgical candidacy. Stone size was categorized as small (0–4 mm), medium (5–7 mm), and large (≥ 8 mm). Results At the time of ERCP, 37 (20.1%) patients had sludge only, 96 (52.2%) had stones only, 42 (22.8%) had sludge and stones, and 9 (4.8%) had no stones. Of the 138 patients with any stones, 37 (26.8%) had small stones, 41 (29.7%) medium, 43 (31.2%) large, and 17 (12.3%) had uncharacterizable stones. Overall, 74.3% of patients had findings of sludge, stones (0–7 mm), or negative ERCP. Conclusion The majority of patients who underwent preoperative ERCP for suspected choledocholithiasis had findings that are amenable to simple intraoperative interventions. In fact, over a quarter of the patients had a negative ERCP, sludge, or small stones which would likely be cleared by flushing/glucagon precluding any further instrumentation. While large stones may require more advanced techniques, this represents a small percentage of patients. 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Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Surgical endoscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sanin, Gloria</au><au>Cambronero, Gabriel</au><au>Patterson, James</au><au>Bosley, Maggie</au><au>Ganapathy, Aravindh</au><au>Wescott, Carl</au><au>Neff, Lucas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>ERCP findings provide further justification for a “surgery-first” mindset in choledocholithiasis</atitle><jtitle>Surgical endoscopy</jtitle><stitle>Surg Endosc</stitle><addtitle>Surg Endosc</addtitle><date>2023-11-01</date><risdate>2023</risdate><volume>37</volume><issue>11</issue><spage>8714</spage><epage>8719</epage><pages>8714-8719</pages><issn>0930-2794</issn><eissn>1432-2218</eissn><abstract>Introduction Choledocholithiasis is most often managed in a two-procedure pathway including endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic cholecystectomy (LC). In contrast, a single-stage, surgery-first approach consisting of LC, cholangiogram, and laparoscopic common bile duct exploration (LCBDE) is associated with reduced hospital stays and equivalent morbidity. Despite this, nationwide referral patterns heavily favor ERCP, obscuring those undergoing ERCP with obstructions amenable to simple intraoperative interventions. We hypothesized that most patients had endoscopic findings consistent with simple sludge or small-to-medium stones, which could have been cleared by basic LCBDE maneuvers. Methods We retrospectively reviewed 294 patients &gt; 18 years old who underwent preoperative ERCP for the management of suspected choledocholithiasis. Exclusion criteria included: failed ERCP, cholangitis, prior cholecystectomy, patient refusal of surgery, or medical conditions precluding surgical candidacy. Stone size was categorized as small (0–4 mm), medium (5–7 mm), and large (≥ 8 mm). Results At the time of ERCP, 37 (20.1%) patients had sludge only, 96 (52.2%) had stones only, 42 (22.8%) had sludge and stones, and 9 (4.8%) had no stones. Of the 138 patients with any stones, 37 (26.8%) had small stones, 41 (29.7%) medium, 43 (31.2%) large, and 17 (12.3%) had uncharacterizable stones. Overall, 74.3% of patients had findings of sludge, stones (0–7 mm), or negative ERCP. Conclusion The majority of patients who underwent preoperative ERCP for suspected choledocholithiasis had findings that are amenable to simple intraoperative interventions. In fact, over a quarter of the patients had a negative ERCP, sludge, or small stones which would likely be cleared by flushing/glucagon precluding any further instrumentation. While large stones may require more advanced techniques, this represents a small percentage of patients. Surgery-first management for suspected choledocholithiasis can offer an efficient alternative for the majority of patients.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>37524916</pmid><doi>10.1007/s00464-023-10329-x</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-0435-1601</orcidid></addata></record>
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subjects 2023 SAGES Oral
Abdominal Surgery
Adolescent
Cholangiography - methods
Cholangiopancreatography, Endoscopic Retrograde - methods
Cholecystectomy
Cholecystectomy, Laparoscopic - methods
Choledocholithiasis - diagnostic imaging
Choledocholithiasis - surgery
Endoscopy
Gastroenterology
Gynecology
Hepatology
Humans
Laparoscopy
Medicine
Medicine & Public Health
Proctology
Retrospective Studies
Sewage
Sludge
Surgery
title ERCP findings provide further justification for a “surgery-first” mindset in choledocholithiasis
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