Garlic-derived exosome-like nanovesicles alleviate dextran sulphate sodium-induced mouse colitis via the TLR4/MyD88/NF-κB pathway and gut microbiota modulation

Plant-derived exosome-like nanovesicles play an important role in transferring their biological cargos to recipient cells. The effect of garlic-derived exosome-like nanovesicles (GENs) against inflammatory bowel disease (IBD) remains unknown. This study aimed to investigate the effect of GENs on dex...

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Veröffentlicht in:	Food & function 2023-08, Vol.14 (16), p.7520-7534
Hauptverfasser:	Zhu, Zhenzhu, Liao, Liuyue, Gao, Mingwei, Liu, Qin
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Colitis Colon Cytokines Damage Dextran Dextrans Digestive system Garlic Gastrointestinal tract Inflammatory bowel disease Inflammatory bowel diseases Intestinal microflora Intestine Lipids Microbiota Microorganisms MicroRNAs miRNA MyD88 protein NF-κB protein Plants Pretreatment Proteins Relative abundance Signal transduction Sodium Sulfates TLR4 protein Toll-like receptors
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