G protein-coupled estrogen receptor 1 deficiency impairs adult hippocampal neurogenesis in mice with schizophrenia

This study aimed to confirm that G protein-coupled estrogen receptor 1 (GPER1) deficiency affects cognitive function by reducing hippocampal neurogenesis via the PKA/ERK/IGF-I signaling pathway in mice with schizophrenia (SZ). Mice were divided into four groups, namely, KO Con, WT Con, KO Con, and W...

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Veröffentlicht in:	Journal of chemical neuroanatomy 2023-10, Vol.132, p.102319, Article 102319
Hauptverfasser:	Zhang, Chun, Niu, Jian-Guo, Kong, Xue-Rui, Mi, Xiao-Juan, Liu, Qiang, Chen, Fei-Fei, Rong, Wei-Fang, Liu, Juan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult hippocampal neurogenesis Cognitive impairment Dizocilpine maleate G protein-coupled estrogen receptor 1 Schizophrenia
Online-Zugang:	Volltext
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