C-X-C motif chemokine ligand 12 improves the developmental potential of bovine oocytes by activating SH2 domain-containing tyrosine phosphatase 2 during maturation

In vitro maturation of mammalian oocytes is an important means in assisted reproductive technology. Most bovine immature oocytes complete nuclear maturation, but less than half develop to the blastocyst stage after fertilization. Thus, inefficient in vitro production is mainly caused by a suboptimal...

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Veröffentlicht in:	Biology of reproduction 2023-09, Vol.109 (3), p.282-296
Hauptverfasser:	Zhang, Min, Zhang, Jingcheng, Wang, Debao, Liu, Zhengqing, Xing, Kangning, Wang, Yongsheng, Jiao, Mei, Wang, Yong, Shi, Binqiang, Zhang, Hexu, Zhang, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell culture Cell number Chemokines Cloning CXCL12 Fertilization in vitro maturation Kinases Ligands MAP kinase MAPK Maturation oocyte quality Oocytes Parthenogenesis Phosphatase Protein biosynthesis Protein-tyrosine-phosphatase Reproductive technologies RESEARCH ARTICLE SHP2 Signal transduction Transcriptomes
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