ADY tripeptide is a minimum sequence for Tyrosylprotein sulfotransferases 1 and 2 substrate recognition

Tyrosylprotein sulfotransferases (TPSTs) catalyze the transfer of a sulphonate moiety from 3′-Phosphoadenosine 5′-Phosphosulfate (PAPS) to the hydroxyl group of a tyrosine residue in substrate proteins. The positively charged substrate binding region of TPST homodimer interacts with acidic residues...

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Veröffentlicht in:Biochemical and biophysical research communications 2023-10, Vol.676, p.73-77
Hauptverfasser: Hasegawa, Yuta, Tonsho, Sayaka, Nakazawa, Taiyo, Kainuma, Tadashi, Kagasaki, Kaori, Sakurai, Shota, Kitagawa, Kouki, Asada, Shinichi
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Sprache:eng
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