Catechol‐O ‐methyltransferase inhibition with entacapone: Evidence from controlled clinical trials in Parkinson's disease

Adjunct therapy with the catechol‐O‐methyltransferase inhibitor entacapone is a first‐line approach to treat wearing‐off type motor fluctuations in levodopa‐treated Parkinson's disease (PD) patients. Five randomized placebo‐controlled trials including a total of >1000 patients have establish...

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Veröffentlicht in:	European journal of neurology 2023-11, Vol.30 (S2), p.9-14
1. Verfasser:	Poewe, Werner
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of daily living Catechol Clinical trials Colitis Diarrhea Dopamine receptors Effectiveness Fluctuations Health services Levodopa Methyltransferase Motor task performance Movement disorders Neurodegenerative diseases Parkinson's disease Patients Quality of life Signs and symptoms
Online-Zugang:	Volltext
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