Redirecting the JAK‐STAT signal blocks the SARS‐CoV‐2 replication

The distinct disease progression patterns of severe acute respiratory syndrome coronavirus clade 2 (SARS‐CoV‐2) indicate diverse host immune responses. SARS‐CoV‐2 severely impairs type I interferon (IFN) cell signaling, resulting in uncontrolled late‐phase lung damage in patients. For better pharmac...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of medical virology 2023-07, Vol.95 (7), p.e28965-n/a
Hauptverfasser:	Augustine, George, Sisila, Valappil, Indhu, Mohan, Gupta, Divya, Tandel, Dixit, Harshan, Krishnan Harinivas, Shanmugam, Ganesh, Padmapriya, Padmanabhan, Sivasubramanian, Srinivasan, Kaveri, Krishnaswamy, Ramudu, Kamini Numbi, Ayyadurai, Niraikulam
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological activity Cell Membrane Cell signaling Coronaviruses COVID-19 Cytokines Disease Progression Genetic code genetic code expansion Humans Immune response Interferon interferon‐β JAK‐STAT pathway Respiration SARS-CoV-2 Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 STAT2 Stat2 protein Tyrosine unnatural amino acid Viral diseases Virology virus Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!