Transcriptome data‐based status of PI3K/AKT/mTOR pathway indicates heterogeneity and immune modulation in patients with pancreatic ductal adenocarcinoma

Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer with limited treatment options. The PI3K/AKT/mTOR pathway is commonly activated in PDAC and plays a critical role in its progression. Methods and Results In this study, the effect of taselisib (a selective PI3K inhibitor) o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The journal of gene medicine 2024-01, Vol.26 (1), p.e3570-n/a
Hauptverfasser:	Xie, Peng, Tan, Si‐Yuan, Li, Hai‐Feng, Tang, Hao‐Dong, Zhou, Jia‐hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Pancreatic Ductal - genetics CD8-Positive T-Lymphocytes - metabolism Cell Proliferation - genetics Humans immune microenvironment machine learning pancreatic ductal adenocarcinoma Pancreatic Neoplasms - metabolism Phosphatidylinositol 3-Kinases - genetics Phosphatidylinositol 3-Kinases - metabolism PI3K/AKT/mTOR prognosis Proto-Oncogene Proteins c-akt - genetics Proto-Oncogene Proteins c-akt - metabolism TOR Serine-Threonine Kinases - genetics TOR Serine-Threonine Kinases - metabolism Transcriptome Tumor Microenvironment
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!