Genome Doubling Shapes High-Grade Transformation and Novel EWSR1::LARP4 Fusion Shows SOX10 Immunostaining in Hyalinizing Clear Cell Carcinoma of Salivary Gland

Hyalinizing clear cell carcinoma (HCCC) is a rare indolent malignant tumor of minor salivary gland origin with EWSR1::ATF1 rearrangement. Pathologically, the tumor cells possess a clear cytoplasm in a background of hyalinized stroma. Generally, the tumor cells are positive for p63 and p40 and negati...

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Veröffentlicht in:	Laboratory investigation 2023-10, Vol.103 (10), p.100213-100213, Article 100213
Hauptverfasser:	Kobayashi, Kenya, Kawazu, Masahito, Yoshimoto, Seiichi, Ueno, Toshihide, Omura, Go, Saito, Yuki, Ando, Mizuo, Ryo, Eigitsu, Sakyo, Airi, Yoshida, Akihiko, Yatabe, Yasushi, Mano, Hiroyuki, Mori, Taisuke
Format:	Artikel
Sprache:	eng
Schlagworte:	EWSR1 genome doubling high-grade transformation hyalinizing clear cell carcinoma LARP4 novel fusion
Online-Zugang:	Volltext
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