The inhibitory effects of live and UV-killed Akkermansia muciniphila and its derivatives on cytotoxicity and inflammatory response induced by Clostridioides difficile RT001 in vitro

Clostridioides difficile infection (CDI) is the leading cause of healthcare-acquired infections worldwide. Probiotics are widely recommended to prevent CDI and its recurrences. Akkermansia muciniphila , as a therapeutic symbiont colonizing the intestinal mucosal layer, is considered to be a promisin...

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Veröffentlicht in:	International microbiology 2024-04, Vol.27 (2), p.393-409
Hauptverfasser:	Nasiri, Gelareh, Azimirad, Masoumeh, Goudarzi, Hossein, Amirkamali, Sahar, Yadegar, Abbas, Ghalavand, Zohreh, Shahrokh, Shabnam, Asadzadeh Aghdaei, Hamid, Zali, Mohammad Reza
Format:	Artikel
Sprache:	eng
Schlagworte:	Akkermansia Akkermansia muciniphila Applied Microbiology Biomedical and Life Sciences Caco-2 Cells Cell viability Clostridioides difficile Cytotoxicity Eukaryotic Microbiology Humans Inactivation Inflammation Inflammatory response Life Sciences Linoleic Acids Medical Microbiology Microbial Ecology Microbiology Probiotics Toxicity Tumor necrosis factor-α
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