MiR-223-3p attenuates radiation-induced inflammatory response and inhibits the activation of NLRP3 inflammasome in macrophages

[Display omitted] •Radiation induce ANA-1 cells pyroptosis through NLRP3/caspase-1/GSDMD signaling axis.•Nlrp3 gene knockout aggravated radiation-induced pyroptosis in ANA-1 cells.•High-throughput sequencing to screen potential miRNAs contributing to post-transcriptional regulation of NLRP3.•MiR-223...

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Veröffentlicht in:	International immunopharmacology 2023-09, Vol.122, p.110616-110616, Article 110616
Hauptverfasser:	Zhang, Mingwei, Lan, Hailin, Peng, Shaoli, Zhou, Weitong, Wang, Xuezhen, Jiang, Meina, Hong, Jinsheng, Zhang, Qiuyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Macrophage miR-223-3p NLRP3 inflammasome Pyroptosis Radiation
Online-Zugang:	Volltext
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